Sema4 Noninvasive Prenatal Select screens for chromosomal abnormalities associated with common genetic conditions, such as Down syndrome. In addition, it may also test for other chromosomal abnormalities. If you would like to know, Sema4 Noninvasive Prenatal Select can reveal the sex of your baby as early as nine weeks into pregnancy.
There are four different panels for Noninvasive Prenatal Select that your healthcare provider can order:
- The Standard Panel screens for commonly identified chromosome abnormalities, including trisomy 21 (Down syndrome), trisomy 18, and trisomy 13
- The Standard Panel with Sex Chromosome Aneuploidies (SCA) includes all abnormalities covered by the Standard Panel and sex chromosome abnormalities (extra or missing sex chromosomes)
- The Standard Plus Panel includes all abnormalities covered by the Standard Panel. It also screens for trisomy 15, trisomy 16, trisomy 22, and sex chromosome abnormalities (extra or missing sex chromosomes)
- The Expanded Panel includes all abnormalities covered by the Standard Plus Panel. It also screens for specific conditions resulting from missing pieces of chromosomes, called microdeletions
Each of these panels can also provide information about the sex of the baby. To learn more about which panel below may be right for you, please talk to your healthcare provider.
- Standard: Trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), and trisomy 13 (Patau syndrome)
- Standard with Sex Chromosome Aneuploidies (SCA): Trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome), monosomy X (Turner syndrome), XXX (Trisomy X syndrome), XXY (Klinefelter syndrome), and XYY syndrome
- Standard Plus: Trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome), trisomy 15, trisomy 16, trisomy 22, monosomy X (Turner syndrome), XXX (Trisomy X syndrome), XXY (Klinefelter syndrome), and XYY syndrome
- Expanded: Trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), trisomy 13 (Patau syndrome), trisomy 15, trisomy 16, trisomy 22, monosomy X (Turner syndrome), XXX (Trisomy X syndrome), XXY (Klinefelter syndrome), XYY syndrome, 22q11.2 deletion, 1p36 deletion, 4p16 deletion (Wolf-Hirschhorn syndrome), 5p15 deletion (Cri-du-chat syndrome), 15q11.2-q13 deletion (Prader-Willi or Angelman syndrome), 11q23 deletion (Jacobsen syndrome), and 8q24 deletion (Langer-Giedion syndrome)